Which organism is Stenotrophomonas maltophilia most susceptible to, guiding therapy with Bactrim as DOC?

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Multiple Choice

Which organism is Stenotrophomonas maltophilia most susceptible to, guiding therapy with Bactrim as DOC?

Stenotrophomonas maltophilia has a distinctive resistance pattern that makes it resistant to many common antibiotics, so trimethoprim-sulfamethoxazole (Bactrim) remains the most reliable option. Because this organism is typically susceptible to TMP-SMX while other pathogens are not as reliably treated by it, TMP-SMX is the drug of choice for infections caused by S. maltophilia. That’s why this organism is the best match for therapy guided by Bactrim. In comparison, Enterococcus faecalis and Pseudomonas aeruginosa often show resistance to TMP-SMX, and Escherichia coli can be either susceptible or resistant depending on the strain, but TMP-SMX isn’t the preferred, consistently effective choice for those infections.

Stenotrophomonas maltophilia has a distinctive resistance pattern that makes it resistant to many common antibiotics, so trimethoprim-sulfamethoxazole (Bactrim) remains the most reliable option. Because this organism is typically susceptible to TMP-SMX while other pathogens are not as reliably treated by it, TMP-SMX is the drug of choice for infections caused by S. maltophilia. That’s why this organism is the best match for therapy guided by Bactrim. In comparison, Enterococcus faecalis and Pseudomonas aeruginosa often show resistance to TMP-SMX, and Escherichia coli can be either susceptible or resistant depending on the strain, but TMP-SMX isn’t the preferred, consistently effective choice for those infections.

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