Delafloxacin is notable for activity against which resistant organism?

Prepare for the Antibacterials (ABX) Exam. Study with flashcards and multiple-choice questions, each question comes with hints and explanations. Get ready to ace your test!

Multiple Choice

Delafloxacin is notable for activity against which resistant organism?

Explanation:
Delafloxacin is notable for activity against MRSA. MRSA is resistant to many antibiotics, and older fluoroquinolones often fail to treat infections caused by these resistant strains. Delafloxacin, a newer fluoroquinolone, retains potent activity against MRSA by effectively inhibiting both DNA gyrase and topoisomerase IV in these bacteria and by overall stronger Gram-positive activity. The other fluoroquinolones listed typically do not reliably cover MRSA, so delafloxacin stands out for this resistance pattern.

Delafloxacin is notable for activity against MRSA. MRSA is resistant to many antibiotics, and older fluoroquinolones often fail to treat infections caused by these resistant strains. Delafloxacin, a newer fluoroquinolone, retains potent activity against MRSA by effectively inhibiting both DNA gyrase and topoisomerase IV in these bacteria and by overall stronger Gram-positive activity. The other fluoroquinolones listed typically do not reliably cover MRSA, so delafloxacin stands out for this resistance pattern.

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