Prepare for the Antibacterials (ABX) Exam. Study with flashcards and multiple-choice questions, each question comes with hints and explanations. Get ready to ace your test!

Multiple Choice

Clindamycin covers which types of bacteria?

Clindamycin works best against anaerobes and many Gram‑positive cocci, including community-associated MRSA. It does not reliably cover Gram‑negative rods, Pseudomonas, or atypical pathogens, which is why the correct grouping is anaerobes plus CA‑MRSA. Mechanistically, it inhibits the 50S ribosomal subunit, which helps explain its strong anaerobic and certain Gram‑positive activity, while Gram‑negative organisms and atypicals are not effectively targeted.

Clindamycin works best against anaerobes and many Gram‑positive cocci, including community-associated MRSA. It does not reliably cover Gram‑negative rods, Pseudomonas, or atypical pathogens, which is why the correct grouping is anaerobes plus CA‑MRSA. Mechanistically, it inhibits the 50S ribosomal subunit, which helps explain its strong anaerobic and certain Gram‑positive activity, while Gram‑negative organisms and atypicals are not effectively targeted.