Aztreonam spectrum activity: which organism group does it primarily cover?

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Multiple Choice

Aztreonam spectrum activity: which organism group does it primarily cover?

Aztreonam is a monobactam that inhibits cell wall synthesis and has a narrow spectrum focused on Gram-negative aerobic bacteria. This means it effectively targets Gram-negative rods (including many Pseudomonas species) but does not work against Gram-positive cocci or anaerobic bacteria. The structure and binding properties of aztreonam limit its activity to Gram-negative aerobes, making it inactive against Gram-positives and anaerobes. Therefore, the statement that best describes its spectrum is that it covers Gram-negative aerobic bacteria and is inactive against Gram-positive and anaerobes.

Aztreonam is a monobactam that inhibits cell wall synthesis and has a narrow spectrum focused on Gram-negative aerobic bacteria. This means it effectively targets Gram-negative rods (including many Pseudomonas species) but does not work against Gram-positive cocci or anaerobic bacteria. The structure and binding properties of aztreonam limit its activity to Gram-negative aerobes, making it inactive against Gram-positives and anaerobes. Therefore, the statement that best describes its spectrum is that it covers Gram-negative aerobic bacteria and is inactive against Gram-positive and anaerobes.

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